Discuss the function in detail of each of the following RNA polymerase II transcription factors. (8 points, 2 points each) TFIIB TFIIE TFIIF TFIIH What additional role does one of the subunits of TFIIH have during the initiation phase that involves other protein kinases? What is the end result? (2 points) Discuss in detail how the 5â€™ cap is formed in eukarytotic mRNAs. (4 points) What makes the 3â€™ end of eukaryotic mRNAs unique? Describe how this is added. (3 points) What are the five snRNAs involved in splicing reaction, and describe briefly how they work to assemble spliceosomes. (3 points)
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